Successful plasma exchange in type 1 leprosy reversal reaction.
نویسندگان
چکیده
منابع مشابه
Successful plasma exchange in type 1 leprosy reversal reaction.
A 24 year old man admitted to hospital with borderline lepromatous leprosy was treated with rifampicin, dapsone, and clofazimine. After four months he developed a reversal reaction and the diagnosis was modified to borderline tuberculoid leprosy. The dose of clofazimine was raised and prednisolone added to the regimen without any symptomatic response. His condition improved dramatically after f...
متن کاملDiagnosis and treatment of leprosy type 1 (reversal) reaction.
Leprosy is a chronic granulomatous infection caused by the organism Mycobacterium leprae that primarily affects the skin and peripheral nerves. Leprosy has several distinct clinical presentations ranging from moderate to severe, with the extent of disease generally depending on the host's immune response to the infection. Treatment typically involves antimicrobials (eg, clofazimine, dapsone, ri...
متن کاملHistoid leprosy with Type 1 reaction
A sixty-one years old man presented with multiple nodules and plaques of different sizes, distributed on the face, trunk, buttocks and lower extremities. He had a history of prior treatment with dapsone monotherapy for Lepromatous leprosy (LL) thirty years ago. The patient was diagnosed with Histoid Borderline-Lepromatous Leprosy after clinical examination and the results of slit skin smears an...
متن کاملType 1 leprosy reversal reaction treated with topical tacrolimus along with systemic corticosteroids.
An 11-year-old black Haitian boy presented with borderline lepromatous leprosy and was treated with rifampicin, dapsone, and clofazimine. After 4 months he developed a severe type 1 reversal reaction without nerve involvement. He was started on prednisolone (1 mg/kg daily). After 4 weeks of treatment with corticosteroids, his condition did not improve and the lesions remained painful. The patie...
متن کاملMethotrexate treatment for type 1 (reversal) leprosy reactions.
Corticosteroids are the drugs of choice for treatment of type 1 leprosy reactions, but when these agents cannot be used because of their adverse effects, alternative treatments are needed. We report the first case, to our knowledge, of a type 1 leprosy reaction that was successfully treated with methotrexate in a patient intolerant to corticosteroids who had borderline lepromatous leprosy.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: BMJ
سال: 1984
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.289.6459.1647